Cardiovascular risk scores and prescribing in diabetes

Potential Effect of Opium Consumption on Controlling Diabetes and Some Cardiovascular Risk Factors in Diabetic Patients

Background: Due to this belief that opium may have beneficial effects on diabetes or cardiovascular risk factors, the present study aimed to assess the potential and possible effects of opium consumption on diabetes control and some cardiovascular risk factors in diabetic patients. Methods: This study enrolled 374 diabetic subjects from diabetes care centers in Kerman, Iran including opium user...

On validation of cardiovascular risk scores.

In predictive modeling, as reviewed by these authors, historical data are used to predict a known future. Each model produces a risk score on a scale of 0-1 (or 0-100%), but each outcome is either an event or a non-event, so the score cannot ever be “valid”, except in an extreme situation. As in many of the papers reviewed, typically the basic definition of “validation” is stretched to include ...

Cardiovascular risk scores in relation to social deprivation and ethnicity.

Epigenetic Changes in Diabetes and Cardiovascular Risk.

Cardiovascular complications remain the leading causes of morbidity and premature mortality in patients with diabetes mellitus. Studies in humans and preclinical models demonstrate lasting gene expression changes in the vasculopathies initiated by previous exposure to high glucose concentrations and the associated overproduction of reactive oxygen species. The molecular signatures of chromatin ...

Psychosocial Factors in Diabetes and Cardiovascular Risk

Type 2 diabetes is a chronic disease that is increasing in prevalence globally. Cardiovascular disease is a major cause of mortality and morbidity in diabetes, and lifestyle and clinical risk factors do not fully account for the link between the conditions. This article provides an overview of the evidence concerning the role of psychosocial stress factors in diabetes risk, as well as in cardio...